PC 707 Study guides, Class notes & Summaries

IgE mediated allergic reaction that happens after the 2nd exposure to the antigen? - Type I Immediate hypersensitivity Delayed Allergic reaction involving T cell in the skin? - Type IV Reaction Primary treatment for a Type 1 Allergic response? - Epinephrine Adjunctive treatment for a Type 1 Allergic response - ‣ H1 Blockers ‣ Corticosteroids help prevent bi phasic reactions ‣ Bronchodilators provide some reliefOne of the most Severe forms of a Type IV allergic reactions. - ‣ Stev...

IgE mediated allergic reaction that happens after the 2nd exposure to the antigen? - Answer-Type I Immediate hypersensitivity Delayed Allergic reaction involving T cell in the skin? - Answer-Type IV Reaction Primary treatment for a Type 1 Allergic response? - Answer-Epinephrine Adjunctive treatment for a Type 1 Allergic response - Answer-‣ H1 Blockers ‣ Corticosteroids help prevent bi phasic reactions ‣ Bronchodilators provide some reliefOne of the most Severe forms of a Type IV alle...

For quick relief of Anxiety - Answer 2 wk course of intermediate acting benzodiazepine PRN Q 8 hrs. Buspirone (BuSpar) - Answer o Not habit forming o Not a CNS depressant o MOA • Mostly unknown • High affinity for serotonin & lesser affinity for dopamine receptors Hydroxyzine (Atarax, Vistaril) - Answer o No abuse or addiction concerns o Strong antihistamine • Anticholinergic effects

ASA - Answer clotting/ anti-inflammatory/ antipyretic inhibits cox 1&2 Contraindications: renal impairment GI bleeds other antiplatelet/ anticoagulant glucocorticoids Alcohol NSAIDS ACEI BBW: GI bleed what is the BBW for aspirin - Answer Increased risk of GI bleed

PCN MOA - Answer inhibitor of cell wall synthesis. Works by weakening the organism cell wall causing excessive amt of H2O to be taken up & rupturing the cell wall, thus disrupting cell wall synthesis & promoting its destruction. Is PCN bacteriostatic or bactericidal? - Answer bactericidal PCN is aerobic or anaerobic? - Answer anaerobic Gm pos or neg? including? These are abx chosen for? - Answer positive; enterococci, streptococci, & non-penicillinase stphylococci;

What is the first line oral diabetic medicaiton? - Answer Biguanides (Metformin) What is the MOA of Biguanides? - Answer Increases insulin action by suppressing glucose output from the liver, enhancing receptor sensitivity to insulin in muscle and fat, reduces glucose absorption in the gut What are the potential side effects of Biguanides? - Answer Metallic taste in mouth, mild anorexia, nausea, abd discomfort, diarrhea What are the adverse effects of Biduanides? - Answer Lactic acidosis

What type of diabetes is the result of autoimmune induced pancreatic beta cell destruction resulting in insulin deficiency? - Answer Type I DM Jenna, a 67 yo diabetic female was admitted to the ER with the following signs: Dehydration Abdominal pain Vomiting Decreased level of consciousness What is going on with Jenna? - Answer DKA

Are the tow typeof CCBs mechanisms of action different? - Answer Dihydrophyridines: slow down the heart rate; Type 1 CCB: depress the muscles of the heart How do they differ in adverse effects? - Answer Dihydrophyridines (short acting) have a higher rate of adverse effects Are there certain indications of when to choose one CCB over the other? - Answer Long acting forms are suggested, however cost must considered to ensure compliance, extended release diltiazem is the most expensive, amlod...

Which 4 categories of medications result in vasodilation? ACEi, ARB, ARNi DRI and CCB (DHP), nitroglycerin ACEi end in Pril ARB end in artan Concerns with ACE meds? Angioedema, hyperkalemia, dry hacking cough and renal injury Drug to drug interactions for ACEi? Other hypotensive agents, meds that also increase K+ and NSAIDS Drug to drug interactions for ARB? Other hypotensive agents and medications that increase K+ Concerns with ARB? Angioedema, hyperkalemia and renal injury What m...

Type 1 DM-Basics - Answer Result of autoimmune induced pancreatic beta cell destruction with resulting insulin deficiency Usually occurs in persons <30 years of age Symptomatic presentation: involuntary weight loss polyuria polydipsia polyphagia DM-Diagnostic Tests - Answer A1c

IgE mediated allergic reaction that happens after the 2nd exposure to the antigen? - Type I Immediate hypersensitivity Delayed Allergic reaction involving T cell in the skin? - Type IV Reaction Primary treatment for a Type 1 Allergic response? - Epinephrine Adjunctive treatment for a Type 1 Allergic response - ‣ H1 Blockers ‣ Corticosteroids help prevent bi phasic reactions ‣ Bronchodilators provide some reliefOne of the most Severe forms of a Type IV allergic reactions. - ‣ Stev...

IgE mediated allergic reaction that happens after the 2nd exposure to the antigen? - Type I Immediate hypersensitivity Delayed Allergic reaction involving T cell in the skin? - Type IV Reaction Primary treatment for a Type 1 Allergic response? - Epinephrine Adjunctive treatment for a Type 1 Allergic response - ‣ H1 Blockers ‣ Corticosteroids help prevent bi phasic reactions ‣ Bronchodilators provide some reliefOne of the most Severe forms of a Type IV allergic reactions. - ‣ Stev...